上海浩洋生物科技有限公司

 CELL SHEET MIGRATION INHIB, LOCOSTATIN
  • CELL SHEET MIGRATION INHIB, LOCOSTATIN
  • CELL SHEET MIGRATION INHIB, LOCOSTATIN

    参考价格: ¥2257.00
    品  牌:merck
    产品型号:219469-10MG (10MG)
    所在地区:上海
    上架时间:2013年04月23日
    留言咨询
    与企业取得联系时请告知该信息获取自中国教育装备采购网
    我要分享
    详细说明

    CELL SHEET MIGRATION INHIB, LOCOSTATIN
    产品名称:CELL SHEET MIGRATION INHIB, LOCOSTATIN
    产品货号:219469-10MG
    产品价格:¥2257
    产品规格:10MG
    Background Information: A cell-permeable N-(crotonyl)oxazolidinone compound that acts as a potent inhibitor of Raf kinase inhibitor protein (RKIP)/Raf1 kinase interaction. Shown to block eukaryotic cell migration (IC50 = 14 µM for inhibition of wound closure in MDCK cell monolayers) and decrease formation of lamellipodial protrusions at the wound margin. Also inhibits early development in frog embryos and tissue dynamics in embryonic explants. Displays no antibacterial activity. May serve as a useful tool for studying RKIP-mediated signaling pathways. Although locostatin is an irreversible inhibitor of RKIP, its cellular effects are generally reversible due to new biosynthesis.
    Molecular Weight: 245.3
    Sales Restrictions: Sold under license of U.S. Patent 7,390,826.
    Presentation: White solid. Packaged under inert gas.
    Properties: Solubility: DMSO (5 mg/ml) or Methanol (50 mg/ml).
    Storage Conditions: Shipped at Ambient Temperature. Store at +2 - 8°C.