上海浩洋生物科技有限公司

 CFTR-F508DEL CORRECTOR, KM11060
  • CFTR-F508DEL CORRECTOR, KM11060
  • CFTR-F508DEL CORRECTOR, KM11060

    参考价格: ¥1421.00
    品  牌:merck
    产品型号:219676-5MG (5MG)
    所在地区:上海
    上架时间:2013年04月23日
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    CFTR-F508DEL CORRECTOR, KM11060
    产品名称:CFTR-F508DEL CORRECTOR, KM11060
    产品货号:219676-5MG
    产品价格:¥1421
    产品规格:5MG
    Background Information: A cell-permeable sulfonylpiperazine compound that is shown to boost the surface expression of cellular F508del-CFTR in a time- and dose-dependent manner and help restore CFTR function in F508del-CFTR-expressing cells (Effective concentration 10 µM). Evidence indicates that a correction of trafficking at the level of ER coupled with a transient increase of cellular cGMP due to PDEV (Cat. Nos. 524715 and 524738) inhibition as part of the cellular mechanism that accounts for the observed pharmacological effects of KM11060.
    Purity: ≥97% by HPLC
    Empirical Formula: C19H17Cl2N3O2S
    Presentation: White solid. Packaged under inert gas.
    Molecular Weight: 422.3
    Storage Conditions: Shipped at Ambient Temperature. Store at +2 - 8°C.