Background Information: Synthetic benzothiazepine that acts as an L-type Ca2+ channel antagonist. Similar in function to Nifedipine (Cat. No. 481981) and Verapamil (Cat. No. 676777). Has negative inotropic effects on the heart. Strongly suppresses conductance at the A-V node and automaticity at the S-A node. Has also been shown to regulate Ca2+ release from intracellular stores in neutrophils.
Molecular Weight: 451
Presentation: White solid.
Storage Conditions: Shipped at Ambient Temperature. Store at +15 - 30°C.
Properties: Solubility: H2O (50 mg/ml), Methanol, or chloroform.
Empirical Formula: C22H26N2O4S · HCl
Purity: ≥98% by HPLC