Background Information: A cell-permeable and reversible inhibitor of protein kinase C (PKC; IC50 = 12 µM) and stimulates Src kinase activity. Useful for inhibiting cell surface expression of selectins that promote adhesion of leukocytes or tumor cells to platelets and endothelial cells. Induces apoptosis in human leukemia HL-60 cells. An inhibitor of sphingosine kinase.
Molecular Weight: 327.6
Presentation: Waxy solid/Clear oil.
Properties: Solubility: DMSO (5 mg/ml), Ethanol, or Methanol.
Gene Symbol: PRKCA, PRKCB, PRKCD, PRKCE, PRKCG, PRKCH, PRKCI, PRKCQ, PRKCZ
Empirical Formula: C20H41NO2
Purity: ≥98% by TLC
Storage Conditions: Shipped at Ambient Temperature. Store at -20°C. Protect from moisture.