产品名称：DIPHTHERIA TOXIN, UNNICKED
Background Information: Catalyzes ADP-ribosylation of eukaryotic aminoacyltransferase II (EF2) using NAD as substrate, thereby inhibiting protein synthesis. May also induce internucleosomal breakdown. Causes DNA fragmentation and cytolysis in U937 cells. Activation requires nicking with a protease followed by reduction with DTT.
Purity: Major band (under reducing conditions) of ~63 kDa
Presentation: Solid. Lyophilized from sterile 10 mM Tris, 1 mM EDTA, pH 7.5.
Molecular Weight: 63000
Storage Conditions: Shipped at Ambient Temperature. Store at +2 - 8°C.