Background Information: A potent, cell-permeable, reversible, and ATP-competitive inhibitor of cyclic-nucleotide-dependent protein kinases. Inhibits protein kinase A (Ki = 1.2 µM), myosin light chain kinase (Ki = 68 µM), protein kinase C (Ki = 15 µM), and protein kinase G (Ki = 480 nM).
Empirical Formula: C12H15N3O2S · 2HCl
Gene Symbol: PRKACA, PRKACB, PRKACG, PRKAG1, PRKAG2, PRKAR1A, PRKAR1B, PRKAR2A, PRKAR2B
Molecular Weight: 338.3
Properties: Solubility: H2O (10 mg/ml). Further dilute with aqueous buffer just prior to use.
Storage Conditions: Shipped at Ambient Temperature. Store at +2 - 8°C.