产品名称：JAK3 INHIBITOR I
Background Information: A cell-permeable, reversible, potent, ATP-competitive, and specific inhibitor of JAK3 (Janus family kinase 3; IC50 = 78 µM). Has no effect on JAK1, JAK2, or Zap/Syk or Src tyrosine kinases. Acts as a potent inhibitor of glioblastoma cell adhesion and migration. Also reported to block thrombin-induced platelet aggregation.
Molecular Weight: 297.3
Sales Restrictions: Sold under license of U.S. Patent 6,080,748 and corresponding patents.
Presentation: White to off-white solid. Packaged under inert gas.
Properties: Solubility: DMSO (50 mg/ml).
Empirical Formula: C16H15N3O3
Storage Conditions: Shipped at Ambient Temperature. Store at -20°C.