产品名称：NF-KAPPA B ACTIVATION INHIBITOR III
Background Information: A cell-permeable thiazoloamide compound that inhibits TNF-α-stimulated NF-κB activation and subsequent upregulation of MMP-9 in HT1080 cells (complete inhibition at 10 µM). The inhibition of MMP-9 upregulation correlates with a concomitant inhibition of TNF-α-dependent cell invasion. Does not affect TNF-α-induced AP-1 activity. The cellular target appears to be downstream of p38 activation.
Molecular Weight: 328.7
Presentation: Light yellow amorphous solid. Packaged under inert gas.
Properties: Solubility: DMSO (10 mg/ml).
Gene Symbol: NFKB1, NFKB2
Empirical Formula: C10H5ClN4O5S
Storage Conditions: Shipped at Ambient Temperature. Store at +2 - 8°C.