Background Information: Irreversible inhibitor of serine proteases. Its mechanism of action is analogous to that of diisopropylfluorophosphate. PMSF causes sulfonylation of the active-site serine residues. Also reported to inhibit internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor, see AEBSF (Cat. No. 101500).
Molecular Weight: 174.2
Presentation: White to off-white crystalline solid.
Properties: Solubility: Ethanol, isopropanol, or methanol.
Empirical Formula: C7H7FO2S
Storage Conditions: Shipped at Ambient Temperature. Store at +15 - 30°C. Protect from moisture.