产品名称： Coagulation factor VIIa
background : Factor VIIa (FVIIa) is a key serine protease involved in the initiation of the coagulation cascade. FVIIa requires tissue factor (TF), a membrane bound protein, as an essential cofactor for maximal activity towards its biological substrates Factor X, Factor IX and Factor VII (FVII).
immunogen : recombinant human Factor VIIa (NovoSeven ®, Novo Nordisk A/S Denmark)
antibody format : rabbit; polyclonal; affinity purified total IgG in PBS pH 7.4; lyophilized
quantity : 250 µg - for reconstitution add 250 µl of sterile water
storage : store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please, remember to spin tubes briefly prior to opening them, to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
tested applications prothrombin assay with human plasma (PT), thrombin generation assay, inhibition assay with Factor VIIa with TF and a chromogenic substrate, indirect ELISA (I-ELISA)