上海浩洋生物科技有限公司

anti-human IREM-2 (CD300LE, IREM2) Purified UP-H2

anti-human IREM-2 (CD300LE, IREM2) Purified UP-H2

参考价格:¥2388.00
品  牌:eBioscience
产品型号:14-3007-82 (100 ug)
所在地区:华东 上海
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anti-human IREM-2 (CD300LE, IREM2) Purified UP-H2
产品名称:anti-human IREM-2 (CD300LE, IREM2) Purified UP-H2
规格:100 ug
货号:14-3007-82
厂商:eBioscience
产品介绍:
Also known as: IREM2, CLM-2
Clone: UP-H2
Host Mouse
Isotype IgG1
Reactivity Human
Conjugate Purified
Reported Applications Flow Cytometric Analysis, Immunoprecipitation, Western Blotting
Description: The monoclonal antibody UP-H2 recognizes human IREM-2 (immune receptor expressed in monocytic derived cells) also known as LMIR6, and unofficially CD300E and CD300LE. It is a member of the CMRF-35 family. This 34 kDa Ig-like containing receptor is an activating receptor and through it’s charged residues in the cytokplasmic domain interacts with ITAM containing adaptor proteins like DAP12. Expression is found exclusively on monocytes and myeloid DC’s. Expression may be transient as differentiation of monocytes leads to down regulation of IREM-2 yet expression is found on mature DCs. It has been also noted that myeloid cell lines such as THP-1 and U937 do not express IREM-2.
eBioscience 14-3007-82 anti-human IREM-2 (CD300LE, IREM2) Purified UP-H2 100 ug 2388
eBioscience 14-3007-80 anti-human IREM-2 (CD300LE, IREM2) Purified UP-H2 25 ug 1068