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 anti-human Toll-like receptor 4 (CD284) APC HTA125
  • anti-human Toll-like receptor 4 (CD284) APC HTA125
  • anti-human Toll-like receptor 4 (CD284) APC HTA125

    参考价格: ¥3468.00
    品  牌:eBioscience
    产品型号:17-9917-42 (100 tests)
    所在地区:上海
    上架时间:2012年12月31日
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    anti-human Toll-like receptor 4 (CD284) APC HTA125
    产品名称:anti-human Toll-like receptor 4 (CD284) APC HTA125
    规格:100 tests
    货号:17-9917-42
    厂商:eBioscience
    产品介绍:
    Also known as: TLR-4, toll-like receptor 4
    Clone: HTA125
    Host Mouse
    Isotype IgG2a, kappa
    Reactivity Human
    Conjugate APC
    Laser Red Laser
    Emit 660 nm
    Excite 633 - 647 nm
    Reported Applications Flow Cytometric Analysis
    Description: The HTA125 monoclonal antibody reacts with human Toll-like receptor 4 (TLR4). So far, at least ten members of the Toll family have been identified in humans. This family of type I transmembrane proteins is characterized by an extracellular domain with leucine-rich repeats and a cytoplasmic domain with homology to the type I IL-1 receptor. Two of these receptors, TLR2 and TLR4, are pattern recognition receptors and signaling molecules in response to bacterial lipoproteins and have been implicated in innate immunity and inflammation. TLR4 physically associates with another molecule called MD-2, and together with CD14, this complex is responsible for LPS recognition and signaling. TLR4 is expressed by peripheral blood monocytes. HTA125 has been reported to immunoprecipitate human TLR4 (~100 kDa) from transfected cells. Most TLR cell surface expression, especially TLR1 and TLR4, occurs at low levels on monocytes and at even lower levels on other cell types including granulocytes and immature dendritic cells (iDC). Furthermore, a relatively high degree of variability in TLR surface expression has been reported among normal donors.
    eBioscience 17-9917-42 anti-human Toll-like receptor 4 (CD284) APC HTA125 100 tests 3468
    eBioscience 17-9917-41 anti-human Toll-like receptor 4 (CD284) APC HTA125 25 tests 1548