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 Anti-Human TSLP Receptor PE (1A6)
  • Anti-Human TSLP Receptor PE (1A6)
  • Anti-Human TSLP Receptor PE (1A6)

    参考价格: ¥3348.00
    品  牌:eBioscience
    产品型号:12-5499-42 (100 tests)
    所在地区:上海
    上架时间:2012年12月31日
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    Anti-Human TSLP Receptor PE (1A6)
    产品名称:Anti-Human TSLP Receptor PE (1A6)
    规格:100 tests
    货号:12-5499-42
    厂商:eBioscience
    产品介绍:
    Also known as: thymic stromal derived lymphopoietin receptor, CRLF-2
    Clone: eBio1A6 (1A6)
    Host Mouse
    Isotype IgG2a, lambda
    Reactivity Human
    Conjugate PE
    Laser Blue Laser, Green Laser, Yellow-Green Laser
    Excite 488 - 561 nm
    Reported Applications Flow Cytometric Analysis
    Description: The eBio1A6 monoclonal antibody reacts with human thymic stromal-derived lymphopoietin receptor (TSLPR). TSLPR is an approximately 50 kDa protein with significant similarity to the common gamma-chain. TSLPR complexes with IL-7R alpha (CD127) to form the high affinity receptor that binds thymic stromal-derived lymphopoietin (TSLP). Human TSLPR is expressed by monocytes and CD11c+ dendritic cells, and TSLP binding induces the expression of the Th2 cell-attracting chemokines CCL17 and CCL22. Furthermore, the TSLPR-induced activation of dendritic cells indirectly results in the increased secretion of Th cytokines IL-4, -5 and -13, which may be necessary for the regulation of CD4+ T cell homeostasis. In mice, deficiency of TSLPR has no effect on lymphocyte numbers, whereas double deficiency of TSLPR and common gamma-chain results in fewer lymphocytes than seen in mice deficient in the common gamma-chain alone. The eBio1A6 monoclonal antibody is able to cross-block binding of another anti-human TSLPR monoclonal antibody, 1D8.
    eBioscience 12-5499-42 Anti-Human TSLP Receptor PE (1A6) 100 tests 3348
    eBioscience 12-5499-41 Anti-Human TSLP Receptor PE (1A6) 25 tests 1548