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 anti-mouse B7-DC (CD273) PE TY25
  • anti-mouse B7-DC (CD273) PE TY25
  • anti-mouse B7-DC (CD273) PE TY25

    参考价格: ¥2148.00
    品  牌:eBioscience
    产品型号:12-5986-82 (100 ug)
    所在地区:上海
    上架时间:2013年01月04日
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    anti-mouse B7-DC (CD273) PE TY25
    产品名称:anti-mouse B7-DC (CD273) PE TY25
    规格:100 ug
    货号:12-5986-82
    厂商:eBioscience
    产品介绍:
    Also known as: B7DC, PD-L2, PDL-2, PDL2
    Clone: TY25
    Host Rat
    Isotype IgG2a, kappa
    Reactivity Mouse
    Conjugate PE
    Laser Blue Laser, Green Laser, Yellow-Green Laser
    Emit 575 nm
    Excite 488 - 561 nm
    Reported Applications Flow Cytometric Analysis
    Description: The TY25 monoclonal antibody reacts with mouse B7-DC/PD-L2. B7-DC, a member of the B7 family, has a predicted molecular weight of ~25 kDa and belongs to the Ig superfamily. The mouse B7-DC has a short cytoplasmic tail (4aa). B7-DC is primarily expressed by sub-populations of dendritic cells, monocytes and macrophages. Although B7-DC has structural and sequence similarities to the B7 family, it does not bind CD28/CTLA-4, but binds PD-1. The interactions between PD-1 and B7-DC/PD-L2 have been reported to be involved in costimulation or suppression of T cell proliferation depending on state of cellular activation. TY25 is a useful tool to study the exact function of B7-DC/PD-L2 in APC/T cell interaction and to characterize the expression pattern of this molecule in mouse.
    eBioscience 12-5986-82 anti-mouse B7-DC (CD273) PE TY25 100 ug 2148
    eBioscience 12-5986-83 anti-mouse B7-DC (CD273) PE TY25 200 ug 3828
    eBioscience 12-5986-81 anti-mouse B7-DC (CD273) PE TY25 50 ug 1548