产品名称：anti-mouse CD244.2 (2B4 B6 Alloantigen) Purified eBio244F4
Also known as: B6 Alloantigen
Reported Applications Flow Cytometric Analysis, Western Blotting
Description: Mouse CD244, also known as 2B4, is a receptor belonging to the CD2 family of proteins involved in non-MHC dependent cytotoxicity. Expression is found on natural killer (NK) cells and many NKT cells and CD8+ cells. In C57BL/6 mice, two splice variants exist that differ in the length of the cytoplasmic domain. The long form functions in an inhibitory manner through signaling through SHP-2, while the short form functions in an activating manner. The ligand for CD244 is CD48 which is expressed on all hematopoietic cells. Recent data suggests that CD244 interactions with CD48, but not CD2 interaction with CD48, is essential for IL-2–driven expansion and activation of murine NK cells.
eBioscience 14-2441-82 anti-mouse CD244.2 (2B4 B6 Alloantigen) Purified eBio244F4 100 ug 1308
eBioscience 14-2441-81 anti-mouse CD244.2 (2B4 B6 Alloantigen) Purified eBio244F4 50 ug 828
eBioscience 14-2441-85 anti-mouse CD244.2 (2B4 B6 Alloantigen) Purified eBio244F4 500 ug 2988