上海浩洋生物科技有限公司

 anti-mouse IL-17F PE eBio18F10
  • anti-mouse IL-17F PE eBio18F10
  • anti-mouse IL-17F PE eBio18F10

    参考价格: ¥3708.00
    品  牌:eBioscience
    产品型号:12-7471-82 (100 ug)
    所在地区:上海
    上架时间:2013年01月10日
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    anti-mouse IL-17F PE eBio18F10
    产品名称:anti-mouse IL-17F PE eBio18F10
    规格:100 ug
    货号:12-7471-82
    厂商:eBioscience
    产品介绍:
    Also known as: Interleukin-17F
    Clone: eBio18F10
    Host Rat
    Isotype IgG2a, kappa
    Reactivity Mouse
    Conjugate PE
    Laser Blue Laser, Green Laser, Yellow-Green Laser
    Excite 488 - 561 nm
    Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
    Description: The eBio18F10 antibody reacts with mouse IL-17F. IL-17F is a 37 kD homodimer of the IL-17 family and a signature Th17 marker. Of all the six IL-17 family members, IL-17F and IL-17A share the strongest homology (50% amino acid identity), and the two genes are located in the same chromosomal region. Recent studies have demonstrated coordinated regulation of IL-17A and IL-17F during Th17 differentiation. Expression of IL-17F and IL-17A has been detected in activated human peripheral blood lymphocytes, specifically by activated human CD4+ T cells. In addition to IL-17A, differentiated Th17 cells also produce IL-17F and IL-22 upon re-activation. Like IL-17A, IL-17F has been linked with inflammatory diseases. IL-17F and IL-17A expression has been observed in tissue samples from various autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, psoriasis, inflammatory bowel disease, and asthma. IL-17F treatment of airway epithelium, vein endothelial cells, and fibroblasts has been reported to induce expression of IL-6, IL-8, GRO-α, ENA-78, TGF-β, MCP-1, G-CSF, GM-CSF, and ICAM-1.
    eBioscience 12-7471-82 anti-mouse IL-17F PE eBio18F10 100 ug 3708
    eBioscience 12-7471-80 anti-mouse IL-17F PE eBio18F10 25 ug 1428