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 Anti-Mouse KLRG1 (clone 2F1) eFluor 450
  • Anti-Mouse KLRG1 (clone 2F1) eFluor 450
  • Anti-Mouse KLRG1 (clone 2F1) eFluor 450

    参考价格: ¥3228.00
    品  牌:eBioscience
    产品型号:48-5893-82 (100 ug)
    所在地区:上海
    上架时间:2013年01月11日
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    Anti-Mouse KLRG1 (clone 2F1) eFluor 450
    产品名称:Anti-Mouse KLRG1 (clone 2F1) eFluor 450
    规格:100 ug
    货号:48-5893-82
    厂商:eBioscience
    产品介绍:
    Also known as: MAFA
    Clone: 2F1
    Host Golden Syrian Hamster
    Isotype IgG
    Reactivity Mouse
    Conjugate eFluor 450
    Laser Violet Laser
    Emit 450 nm
    Excite 405 nm
    Reported Applications Flow Cytometric Analysis
    Description: This 2F1 monoclonal antibody reacts with the mouse Killer cell Lectin-like Receptor G1 (KLRG1), also known as Mast cell Function-associated Antigen (MAFA). KLRG1 is a homodimer of glycosylated 30-38 kDa subunits and contains a cytoplasmic motif similar to the immunoreceptor tyrosine-based inhibitory motif (ITIM). Rat MAFA was identified as an antigen specific to rat mast cells; however, the expression of mouse KLRG1/MAFA using 2F1 has not been detected on the surface of mouse mast cell lines, bone marrow-derived mast cells, or peritoneal mast cells. This antigen is expressed on approximately one-third of mouse NK cells and a subset of T cells. MHC class I molecules regulate KLRG1 via interactions with class I-specific inhibitory Ly49 molecules and SHP-1 signaling. Although KLRG1 and Ly49 are both lectin-like inhibitory receptors that are regulated by class I MHC expression, the effects of this on cell surface expression of these molecules are opposing, and the underlying regulatory mechanisms distinct.
    eBioscience 48-5893-82 Anti-Mouse KLRG1 (clone 2F1) eFluor® 450, 100 ug 3228
    eBioscience 48-5893-80 Anti-Mouse KLRG1 (clone 2F1) eFluor® 450, 25 ug 1308