上海浩洋生物科技有限公司

 Anti-Mouse/Human Integrin beta7 PE (FIB504)
  • Anti-Mouse/Human Integrin beta7 PE (FIB504)
  • Anti-Mouse/Human Integrin beta7 PE (FIB504)

    参考价格: ¥2748.00
    品  牌:eBioscience
    产品型号:12-5867-42 (100 tests)
    所在地区:上海
    上架时间:2013年01月15日
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    Anti-Mouse/Human Integrin beta7 PE (FIB504)
    产品名称:Anti-Mouse/Human Integrin beta7 PE (FIB504)
    规格:100 tests
    货号:12-5867-42
    厂商:eBioscience
    产品介绍:
    Also known as: Integrin b7 ITGB7
    Clone: FIB504
    Host Rat
    Isotype IgG2a, kappa
    Reactivity Human, Mouse
    Conjugate PE
    Laser Blue Laser, Green Laser, Yellow-Green Laser
    Emit 575 nm
    Excite 488 - 561 nm
    Reported Applications Flow Cytometric Analysis
    Description: The FIB504 monoclonal antibody reacts with human and mouse integrin beta 7. Integrin beta 7 is a 130 kD glycoprotein which associates with integrin alpha 4 (CD49d) to form the alpha 4 beta 7 integrin LPAM-1, expressed on intraepithelial lymphocytes. It also associates with alpha E (CD103) to form the alpha E beta 7 integrin HML-1, expressed on T cells adjacent to mucosal epithelium and intraepithelial lymphocytes. Main ligands for integrin alpha 4 beta 7 include VCAM-1 (CD106), MAdCAM-1 and fibronectin, while the main ligand of integrin alpha E beta 7 is E-cadherin (CD324). Integrin beta 7 plays an important role in the adhesion of leukocytes to endothelial cells promoting the transmigration of leukocytes to extravascular spaces during the inflammatory response. The FIB504 antibody has been reported to have blocking activity.
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