上海浩洋生物科技有限公司

 anti-mouse/human/rat EGFR Purified Polyclonal
  • anti-mouse/human/rat EGFR Purified Polyclonal
  • anti-mouse/human/rat EGFR Purified Polyclonal

    参考价格: ¥708.00
    品  牌:eBioscience
    产品型号:14-6747-63 (10 ug)
    所在地区:上海
    上架时间:2013年01月15日
    留言咨询
    与企业取得联系时请告知该信息获取自中国教育装备采购网
    我要分享
    详细说明

    anti-mouse/human/rat EGFR Purified Polyclonal
    产品名称:anti-mouse/human/rat EGFR Purified Polyclonal
    规格:10 ug
    货号:14-6747-63
    厂商:eBioscience
    产品介绍:
    Also known as: EGFR, epidermal growth factor
    Clone: Polyclonal
    Host Rabbit
    Isotype IgG
    Reactivity Human, Mouse, Rat
    Conjugate Purified
    Reported Applications Immunohistochemical Staining, Immunoprecipitation, Western Blotting
    Description: The EGFR polyclonal antibody reacts with mouse, human, and rat EGFR. The antibody was raised against the peptide edmddvvdadey, which represents amino acids 1005-1016 and is located near the carboxy terminus of human EGFR. The EFGR family is a group of four structurally similar tyrosine kinases (EGFR, HER2/neu, ErbB-3, and ErbB-4) that dimerize on binding with a number of ligands, including EGF and transforming growth factor alpha (1&2). The 170 kDa epidermal growth factor receptor binds EGF which activates a tyrosine-specific protein kinase activity intrinsic to the receptor (3&4). Epidermal growth factor receptor overexpression is pronounced in virtually all squamous carcinomas and is also found in > or = 65% of large cell and adenocarcinomas. It is not expressed in situ by small cell lung carcinoma. Overexpression of EGFR is one of the earliest and most consistent abnormalities in bronchial epithelium of high-risk smokers (1).
    eBioscience 14-6747-63 anti-mouse/human/rat EGFR Purified Polyclonal 10 ug 708
    eBioscience 14-6747-81 anti-mouse/human/rat EGFR Purified Polyclonal 50 ug 1668