产品名称：anti-mouse/human/rat NFkB p65 Purified Polyclonal
Also known as: NFkB, NFkappaB p65 subunit, RelA, NFKB3
Reactivity Human, Mouse, Rat
Reported Applications Immunohistochemical Staining, Immunoprecipitation, Western Blotting
Description: The polyclonal antibody reacts with mouse, rat, and human NFkB p65; the antibody was raised against a peptide mapping to the carboxy terminus of human NFkB p65. Members of the rel/NFkB family of transcription factors are involved in the regulation of cellular responses, such as growth, development, and the inflammatory response. They share a structural motif known as the rel homology region (RHR), the C-terminal one third of which mediates protein dimerization (2, 6, 8). Complexes of p50 (NF-kB1) or p52 (NF-kB2) are generated through the processing of p105 and p100 precursors, respectively. These are usually associated with members of the Rel family (p65, c-Rel, Rel B). The homo- and heterodimer formed through combinations of NFkB/Rel proteins bind distinct kB sites to regulate the transcription of different genes (7, 9).
eBioscience 14-6731-63 anti-mouse/human/rat NFkB p65 Purified Polyclonal 10 ug 468
eBioscience 14-6731-81 anti-mouse/human/rat NFkB p65 Purified Polyclonal 50 ug 1308