产品名称：Anti-Mouse/Rat Ki-67 (clone SolA15) Purified
Isotype IgG2a, kappa
Reactivity Canine, Human, Mouse, Rat
Reported Applications Immunohistochemical Staining of Frozen Tissue Sections, Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections, Immunocytochemistry
Description: The monoclonal antibody SolA15 recognizes mouse and rat Ki-67, a 300 kDa nuclear protein. Ki-67 is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0). Ki-67 is detected within the nucleus during interphase but redistributes to the chromosomes during mitosis. Ki-67 is used as a marker for determining the growth fraction of a given population of cells. In studies of tumor cells, the “Ki-67 labeling index” refers to the number of Ki-67 positive cells within the population and this is used to predict outcome of particular cancer types. Ki-67 has been shown to interact with the DNA-bound protein chromobox protein homolog 3 (CBX3) (heterochromatin).
eBioscience 14-5698-82 Anti-Mouse/Rat Ki-67 (clone SolA15) Purified, 100 ug 2628
eBioscience 14-5698-80 Anti-Mouse/Rat Ki-67 (clone SolA15) Purified, 25 ug 1068