上海浩洋生物科技有限公司

 anti-human AITR/GITR PE eBioAITR
  • anti-human AITR/GITR PE eBioAITR
  • anti-human AITR/GITR PE eBioAITR

    参考价格: ¥2388.00
    品  牌:eBioscience
    产品型号:12-5875-41 (25 tests)
    所在地区:上海
    上架时间:2012年12月14日
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    anti-human AITR/GITR PE eBioAITR
    产品名称:anti-human AITR/GITR PE eBioAITR
    规格:25 tests
    货号:12-5875-41
    厂商:eBioscience
    产品介绍:
    Also known as: TNFRSF18, activation-inducible TNFR family member
    Clone: eBioAITR
    Host Mouse
    Isotype IgG1, kappa
    Reactivity Human
    Conjugate PE
    Laser Blue Laser, Green Laser, Yellow-Green Laser
    Excite 488 - 561 nm
    Reported Applications Flow Cytometric Analysis
    Description: The monoclonal antibody reacts with human AITR, Activation Inducible TNFR family member, an approximately 25 kDa member of the TNFR superfamily. AITR mRNA is detected in lymph node, peripheral blood leukocytes and weakly in spleen. AITR mRNA expression was upregulated within 24 hour on PMA/ionomycin or PHA stimulated PBMC. At the protein level, AITR is expressed by a small population of activated PBMC. AITR associates with TRAF1, TRAF2 and TRAF3 and induces nuclear factor NF-κB activation via TRAF2. Recently TL6 (AITRL) has been reported as the ligand for AITR. Interaction of AITR with AITRL is important for cross-talk between T lymphocytes and endothelial cells.