产品名称：anti-human alpha beta TCR PE (clone: WT31)
Also known as: abTCR, TCRab
Laser Blue Laser, Green Laser, Yellow-Green Laser
Emit 575 nm
Excite 488 - 561 nm
Reported Applications Flow Cytometric Analysis
Description: This WT31 monoclonal antibody recognizes the human αβ T cell receptor (TCR) complexed with the CD3ε chain. Composed of a 44-kDa α and a 37-kDa β chain, TCR specificity is typically determined by Vα, Jα, Vβ, Dβ, and Jβ gene rearrangement. The TCR is often associated with the CD3 complex, which is composed of at least five polypeptides. The TCR/CD3 complex recognizes and binds to major histocompatibility complex-bound antigen presented by antigen presenting cells such as B cells, dendritic cells, and macrophages. These events lead to T cell activation, resulting in cellular signaling and cytokine production.