上海浩洋生物科技有限公司

Human CD8 (clone OKT8)

Human CD8 (clone OKT8)

参考价格:¥3228.00
品  牌:eBioscience
产品型号:48-0086-42 (100 tests)
所在地区:上海
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Human CD8 (clone OKT8)
产品名称:Human CD8 (clone OKT8)
规格:100 tests
货号:48-0086-42
厂商:eBioscience
产品介绍:
Also known as: CD8 alpha, leu-2a
Clone: OKT8 (OKT-8)
Host Mouse
Isotype IgG2a
Reactivity Human
Conjugate eFluor 450
Laser Violet Laser
Emit 450 nm
Excite 405 nm
Reported Applications Flow Cytometric Analysis
Description: The OKT8 monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 αβ) or as a homodimer (CD8 αα). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T-cell development and activation of mature T cells. Preliminary testing indicates that OKT8 and two other mouse anti-human CD8 antibodies (clone RPA-T8, Cat. No.14-0088 and clone HIT8a, Cat. No.14-0089) do not compete with each other for binding to human peripheral blood leukocytes by flow cytometric analysis, suggesting that they do not bind to similar epitopes or block each other by steric hindrance.
eBioscience 48-0086-42 Human CD8 (clone OKT8), 100 tests 3228
eBioscience 48-0086-41 Human CD8 (clone OKT8), 25 tests 1428