上海浩洋生物科技有限公司

 Human CD8 (clone OKT8)
  • Human CD8 (clone OKT8)
  • Human CD8 (clone OKT8)

    参考价格: ¥3228.00
    品  牌:eBioscience
    产品型号:48-0086-42 (100 tests)
    所在地区:上海
    上架时间:2013年01月21日
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    Human CD8 (clone OKT8)
    产品名称:Human CD8 (clone OKT8)
    规格:100 tests
    货号:48-0086-42
    厂商:eBioscience
    产品介绍:
    Also known as: CD8 alpha, leu-2a
    Clone: OKT8 (OKT-8)
    Host Mouse
    Isotype IgG2a
    Reactivity Human
    Conjugate eFluor 450
    Laser Violet Laser
    Emit 450 nm
    Excite 405 nm
    Reported Applications Flow Cytometric Analysis
    Description: The OKT8 monoclonal antibody reacts with the human CD8a molecule, an approximately 32-34 kDa cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 αβ) or as a homodimer (CD8 αα). A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class I and through its association with protein tyrosine kinase p56lck plays a role in T-cell development and activation of mature T cells. Preliminary testing indicates that OKT8 and two other mouse anti-human CD8 antibodies (clone RPA-T8, Cat. No.14-0088 and clone HIT8a, Cat. No.14-0089) do not compete with each other for binding to human peripheral blood leukocytes by flow cytometric analysis, suggesting that they do not bind to similar epitopes or block each other by steric hindrance.
    eBioscience 48-0086-42 Human CD8 (clone OKT8), 100 tests 3228
    eBioscience 48-0086-41 Human CD8 (clone OKT8), 25 tests 1428