产品名称：Human CNTF receptor, alpha (clone AN-D3)
Also known as: CNTFRa, CNTF Receptor alpha, CNTF Ra
Isotype IgG2a, kappa
Reported Applications Flow Cytometric Analysis, Immunoprecipitation
Description: This AN-D3 monoclonal antibody reacts with human ciliary neurotrophic factor receptor alpha (CNTFR alpha). CNTFR alpha expression is primarily localized to the nervous system and skeletal muscle. Together with gp130 and LIFR beta, this molecule forms the tripartite CNTF receptor complex. These receptor components remain unassociated until CNTF binds CNTFR alpha, which leads to their recruitment. Subsequent activation of the JAK-STAT pathway leads to changes in gene expression that affect cell survival and differentiation. More recently, another cytokine, neuropoietin, has been shown to bind the CNTFR receptor complex to promote nervous system development.
eBioscience 14-1304-82 Human CNTF receptor, alpha (clone AN-D3), 100 ug 2748
eBioscience 14-1304-80 Human CNTF receptor, alpha (clone AN-D3), 25 ug 1068