产品名称：Human Cytokeratin 19 Purified (BA17)
Also known as: CK19, Keratin 19
Isotype IgG1, kappa
Reported Applications Immunohistochemical Staining of Formalin-Fixed Paraffin Embedded Tissue Sections, Immunocytochemistry
Description: This BA17 monoclonal antibody reacts with human cytokeratin 19 (CK19), a 44-kDa type I (acidic) intermediate filament protein that lacks the non-alpha-helical tail domain present in other keratins. Cytokeratins form the intracellular cytoskeletal network that maintains the integrity and stability of cells and tissues. Cytokeratin 19 is expressed in a wide variety of simple and stratified epithelial tissue. Moreover, cytokeratin 19 expression can be induced by vitamin A, SV40 transformation, and cancer. A soluble form of cytokeratin 19 generated by caspase 3 cleavage has also been found to be secreted by cancer cells, thus possibly indicating tumor metastasis. Cytokeratin 19 often exists as a heterodimer with cytokeratin 7, a type II keratin.
eBioscience 14-9898-82 Human Cytokeratin 19 Purified (BA17) 100 ug 2508
eBioscience 14-9898-80 Human Cytokeratin 19 Purified (BA17) 25 ug 1068