产品名称：Human FGF basic (FGF-2) Carrier-Free Recombinant Protein
Also known as: Fibroblast Growth Factor basic, FGF2
Purity Greater than or equal to 98%, as determined by SDS-PAGE
Molecular Mass 20 kDa
Reported Applications Cytokine Bioassays
Description: Fibroblast Growth Factor basic (FGF-b, also known as FGF-2) is a member of the FGF family, a highly conserved family of 16-34 kDa heparin-binding proteins. FGF-b exists in several isoforms, and although they are equally active, only the 18 kDa form is secreted while the 23 kDa form localizes to the nucleus. It lacks the signal sequence peptide necessary for the ER/Golgi pathway, indicating that secretion occurs via an alternate pathway. FGF-b shares four common tyrosine kinase receptors, FGFR 1-4, and require the binding of a second surface protein, the ubiquitously expressed heparan sulfate proteoglycan, in order to fully activate these receptors. FGF family members affect the proliferation, differentiation, mobility, and survival of several cell types, including fibroblasts, osteoblasts, smooth muscle cells, and neuroblasts. FGF-b expression has been detected in several cell types, including fibroblasts, macrophages, endothelial cells, epithelial cells, and neurons.
eBioscience 34-8986-82 Human FGF basic (FGF-2) Carrier-Free Recombinant Protein 100 ug 3900
eBioscience 34-8986-85 Human FGF basic (FGF-2) Carrier-Free Recombinant Protein 500 ug 9900