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 Human FGF basic (FGF-2) Recombinant Protein
  • Human FGF basic (FGF-2) Recombinant Protein
  • Human FGF basic (FGF-2) Recombinant Protein

    参考价格: ¥1800.00
    品  牌:eBioscience
    产品型号:14-8986-80 (25 ug)
    所在地区:上海
    上架时间:2013年01月21日
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    Human FGF basic (FGF-2) Recombinant Protein
    产品名称:Human FGF basic (FGF-2) Recombinant Protein
    规格:25 ug
    货号:14-8986-80
    厂商:eBioscience
    产品介绍:
    Also known as: FGF basic 147, fibroblast growth factor beta
    Reactivity Human
    Purity Greater than or equal to 98%, as determined by SDS-PAGE
    Molecular Mass 20 kDa
    Endotoxin Level Less than 0.01 ng/ug cytokine as determined by the LAL assay.
    Reported Applications Cytokine Bioassays
    Description: Fibroblast Growth Factor basic (FGF-b, also known as FGF-2) is a member of the FGF family, a highly conserved family of 16-34 kDa heparin-binding proteins. FGF-b exists in several isoforms, and although they are equally active, only the 18 kDa form is secreted while the 23 kDa form localizes to the nucleus. They share four common tyrosine kinase receptors, FGFR 1-4, and require the binding of a second surface protein, the ubiquitously expressed heparan sulfate proteoglycan, in order to fully activate these receptors. FGF family members affect the proliferation, differentiation, mobility, and survival of several cell types, including fibroblasts, osteoblasts, smooth muscle cells, and neuroblasts. FGF-b expression has been detected in several cell types, including fibroblasts, macrophages, endothelial cells, epithelial cells, and neurons. It lacks the signal sequence peptide necessary for the ER/Golgi pathway, indicating that secretion occurs via an alternate pathway. They are particularly important in embryonic development as triggers of neurogenesis, angiogenesis, and neovascularization.
    eBioscience 14-8986-80 Human FGF basic (FGF-2) Recombinant Protein 25 ug 1800
    eBioscience 14-8986-62 Human FGF basic (FGF-2) Recombinant Protein 5 ug 600