产品名称：Human IL-29 (IFN lambda 1) Recombinant Protein
Also known as: Interleukin-29
Purity Greater than 98% as determined by SDS-PAGE
Molecular Mass The protein is not methionylated at the N-terminal and has a predicted molecular mass of 20,018. The DTT reduced protein migrates as a 20 kDa band on SDS-PAGE. The non-reduced protein migrates as a 19 kDa protein on non-reduced SDS-PAGE.
Endotoxin Level Less than 0.01 ng/ug cytokine as determined by the LAL assay.
Reported Applications ELISA, Cytokine Bioassays
Description: IFN-λs are a novel family of interferons which mediate the induction of anti-viral protection in a wide variety of cells. The three members of the IFN-λ family are λ1, λ2, and λ3, also known as IL-29, IL-28A, and IL-28B, respectively. IFN-λs share with type I IFNs an intracellular signaling pathway that drives the expression of a common set of IFN-stimulated genes. IFN-lambdas induce multiple biological activities, including the upregulation of class I MHC gene product expression to levels comparable to those induced by IFN-αs. IL-28 and IL-29 are tested for anti-viral activity by challenging the human hepatocellular carcinoma cell line HepG2 with infection by EMC (following pretreatment of the cells with cytokine).