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  • Mouse IL-21 eFluor 660 (Clone: FFA21)

    参考价格: ¥4188.00
    品  牌:eBioscience
    产品型号:50-7211-82 (100 ug)
    所在地区:上海
    上架时间:2013年01月22日
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    Mouse IL-21 eFluor 660 (Clone: FFA21)
    产品名称:Mouse IL-21 eFluor 660 (Clone: FFA21)
    规格:100 ug
    货号:50-7211-82
    厂商:eBioscience
    产品介绍:
    Also known as: Interleulin-21
    Clone: FFA21
    Host Rat
    Isotype IgG2a, kappa
    Reactivity Mouse
    Conjugate eFluor 660
    Laser Red Laser
    Emit 668 nm
    Excite 633 - 647 nm
    Reported Applications Intracellular Staining Followed by Flow Cytometric Analysis
    Description: This FFA21 monoclonal antibody reacts with mouse interleukin-21 (IL-21). IL-21 is a 17 kDa immunomodulatory cytokine produced mainly by NKT, T helper (Th) 17 and T follicular helper (TFH) cells. In TFH cells, IL-21 expression leads to autocrine signaling through the IL-21 receptor (IL-21R) and STAT3, which leads to additional transcriptional activation by Bcl6. As with IFN gamma for Th1, IL-4 for Th2 and IL-17A for Th17, IL-21 is critical for TFH cell effector function. This cytokine plays a role in T cell-dependent B cell differentiation into plasma cells and memory cells, stimulation of IgG production and induction of apoptotic signaling in naïve B cells.
    eBioscience 50-7211-82 Mouse IL-21 eFluor 660 (Clone: FFA21) 100 ug 4188
    eBioscience 50-7211-80 Mouse IL-21 eFluor 660 (Clone: FFA21) 25 ug 1788