产品名称：Arg8-Vasopressin ELISA kit
规格：1 x 96 wells
Use/Stability: Store all components at 4°, except standard and conjugate at -20°.
Alternative Name: AVP
Sensitivity: 3.39 pg/ml (range 4.10 - 1,000 pg/ml)
Application: For the quantitative determination of Arg8-Vasopressin in culture supernatants from any species. Cited sample type includes plasma (ref. 1, 2).
Kit/Set Contains: GxR IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution
Miscellaneous/General: Arginine vasopressin (AVP) is a nonapeptide hormone produced in magnocellular neurons of the hypothalamus, which functions as an antidiuretic in the kidney and systemically as a regulator of vasoconstriction, blood volume, and blood pressure. AVP acts by binding to a set of specific seven transmembrane domain-containing G-protein coupled receptors (GPCR) classified into three groups: V1a (V1), V1b (V3), and V2. V1b receptors stimulate adrenocorticotropic hormone (ACTH) release in the anterior pituitary, but may also participate in corticotropin-releasing hormone (CRH) release by the hypothalamus. The V1b receptor signals through coupling of Gq/11 alpha subunits, activating phospholipase C and release of intracellular Ca2+ via phosphoinositide second messengers. V1b receptor overexpression is a common marker for ACTH-secreting corticotropic adenomas. V2 receptors in the collecting ducts of the kidneys stimulate adenylyl cyclase activity, regulating the reabsorption of water via aquaporin channels.
The Arg8-Vasopressin EIA kit is a colorimetric competitive enzyme immunoassay kit with results overnight 1 hour.. Absorbance is read at 405 nm. Document your results to scientists worldwide, this kit has been cited in numerous peer-reviewed journals for use in a variety of sample types including urine, perfusates, plasma, tissue, and serum. The simple liquid color-coded reagents reduce error.