产品名称：COX activity kit
规格：1 x 96 wells
Sensitivity: 0.147 Units/ml COX-I (range 7.5 - 60 Units/ml)
Application: For the measurement of COX-1 and COX-2 activity.
Use/Stability: Store all components at +4°, except Inhibitors at -20°.
Kit/Set Contains: Microtiter plate, Chemiluminescent substrate, Ibuprofen, Meloxicam
Miscellaneous/General: Cyclooxygenases-1 and 2 (COX-1 and COX-2) also known as Prostaglandin endoperoxide H synthases-1 and 2 are integral membrane proteins which catalyze the first step of prostaglandin, thromboxane, and prostacyclin production from arachidonic acid. The COX-1 and COX-2 enzymes are important pharmacologically as targets of nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin, ibuprofen and the COX-2 inhibitors. Inhibition of cyclooxygenases with NSAIDs acutely reduces inflammation, pain, and fever.
The COX activity kit is the first commercially available non-radioactive COX activity assay. This kit lets you easily evaluate COX I and COX II inhibitors in a convenient 96-well plate based assay with < 7% intra-assay variation.