产品名称：IL-1β (human), ELISA kit
规格：1 x 96 wells
Long Term Storage: -20°C
Alternative Name: Interleukin-1β
Application: For the quantitative determination of IL-1β in plasma, serum, and urine of human origin.
Kit/Set Contains: Microtiter plate, SA-HRP concentrate, SA-HRP dilution buffer, Biotinylated antibody, Standard, Standard diluent, Wash buffer concentrate, TMB Substrate, Stop solution
The interleukin-1 (IL-1) cytokine family consists of IL-1α, IL-1β, and IL-1Rα (receptor antagonist) which are expressed primarily by endothelial cells and activated macrophages. IL-1α and IL-1β elicit pro-inflammatory cytokine production and cellular activation, and are the primary mediators of hypothalamic regulation that results in fever. IL-1α and IL-1βsignals are transmitted via a dual subunit IL-1 receptor composed of IL-1R1 and the IL-1 receptor accessory protein (IL-1RAcP). IL-1RAcP is vital to IL-1 signaling, as it recruits the IL-1 receptor-associated kinase (IRAK) to the receptor complex, initiating NF-κB pathway activation.