上海浩洋生物科技有限公司

 Bmf (NT), pAb
  • Bmf (NT), pAb
  • Bmf (NT), pAb

    参考价格: ¥4200.00
    品  牌:ENZO
    产品型号:ADI-905-184-100 (100 ug)
    所在地区:上海
    上架时间:2013年02月28日
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    Bmf (NT), pAb
    产品名称:Bmf (NT), pAb
    规格:100 ug
    货号:ADI-905-184-100
    厂商:ENZO
    产品介绍:
    Host: Rabbit
    Long Term Storage: +4°C  
    Immunogen: Synthetic peptide corresponding to the sequence near the C-terminus of human Apaf1. The sequence differs from that of mouse Apaf1 by one amino acid.
    Application: Immunocytochemistry
    Western Blot (2µg/ml, HepG2 or 293 cell lysates can be used for positive control)
    Optimal conditions must be determined individually for each application.
    Specificity: Recognizes human and mouse Bmf. Detects a band of ~25kDa by Western blot.
    Purity Detail: Peptide affinity purified.
    Formulation: Liquid. In PBS containing 0.02% sodium azide.
    Miscellaneous/General: Bmf (Bcl-2 modifying factor) is a member of the Bcl-2 family of apoptotic proteins. The BH3 domain in Bmf is required both for binding to Bcl-2 proteins and for triggering apoptosis. In healthy cells, Bmf associates with the Dynein light chain 2 (DLC2), a component of the myosin V motors, and is sequestered by the cells actin cytoskeleton. Disruption of the actin cytoskeleton triggers release and activation of Bmf, initiating the downstream apoptotic program.