产品名称：p53 DINP1 SIP, pAb
Alternative Name: TRP53, tumor protein p53
Long Term Storage: +4°C
Immunogen: Synthetic peptide corresponding to the sequence near the N-terminus of human p53DINP1. The is completely conserved between α and β isoforms.
Application: Immunohistochemistry (2µg/ml)
Western Blot (1-2µg/ml)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human, mouse and rat p53 DINP1 SIP. Detects a band of ~27kDa by Western blot.
Purity Detail: Peptide affinity purified.
Formulation: Liquid. In PBS containing 0.02% sodium azide.
Miscellaneous/General: p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to Mdm2, SV40 T antigen and human Papilloma virus E6 protein. p53 senses DNA damage and facilitates its repair. Mutation involving p53 is found in a wide variety of malignant tumors, including breast, ovary, bladder, colon, lung, and melanoma.