产品名称：Cytochrome c, mAb (2B5.F8)
Long Term Storage: -20°C
Immunogen: Native horse Cytochrome c.
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human, bovine, dog and horse Cytochrome c. Detects a band of ~13kDa by Western blot.
Purity Detail: Protein G affinity purified.
Formulation: Liquid. In sodium phosphate containing 0.1% sodium azide.
Miscellaneous/General: Cytochrome c, which is a critical component of the electron transport chain, is a component of the functional apoptosome. Upon release from the mitochondria, cytochrome c binds to the adaptor proteins Apaf-1 and procaspase-9 to form a cytosolic apoptosome complex. This event results in activation of procaspase-9 and its subsequent cleavage and activation of caspase-3 leading to the degradation of a series of cellular substrates and subsequently cell death.