产品名称：[pSer28]Histone H3, pAb
Long Term Storage: -20°C
Immunogen: Synthetic peptide corresponding to a portion of human Histone H3 phosphorylated at Ser28.
Application: Immunocytochemistry (1:100-1:1000)
Western Blot (1:200-1:2000, ECL)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human Histone H3. Detects a band of ~15-17kDa by Western blot.
Purity Detail: Peptide affinity purified.
Formulation: Liquid. In PBS, pH7.2, containing 50% glycerol.
Miscellaneous/General: The nucleosome is made up of four core histone proteins (H2A, H2B, H3 and H4) and is the primary building block of chromatin. The core histones form an octamer, which is made up of one H3-H4 tetramer and two H2A-H2B dimers. The N-terminal tail of core histones undergoes different post-transcriptional modifications including acetylation, phosphorylation, methylation and ubiquitination. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression.