上海浩洋生物科技有限公司

 Bradykinin receptor B2, pAb
  • Bradykinin receptor B2, pAb
  • Bradykinin receptor B2, pAb

    参考价格: ¥4350.00
    品  牌:ENZO
    产品型号:ADI-905-747-100 (100 ug)
    所在地区:上海
    上架时间:2013年03月04日
    留言咨询
    与企业取得联系时请告知该信息获取自中国教育装备采购网
    我要分享
    详细说明

    Bradykinin receptor B2, pAb
    产品名称:Bradykinin receptor B2, pAb
    规格:100 ug
    货号:ADI-905-747-100
    厂商:ENZO
    产品介绍:
    Alternative Name: B2BKR 
    Host: Rabbit
    Long Term Storage: -20°C  
    Immunogen: Synthetic peptide corresponding to the sequence near the N-terminus of rat bradykinin receptor B2.
    Application: ELISA (Membrane)
    Immunohistochemistry
    Western Blot
    Optimal conditions must be determined individually for each application.
    Specificity: Recognizes mouse and rat bradykinin receptor B2. Predicted MW of ~45kDa. Higher MW species (~50kDa) and intermediates also observed by Western blot which reflect post-translational modification or dimerization of the receptor. Predicted species reactivity based on epitope sequence homology: guinea pig, dog.
    Purity Detail: Peptide affinity purified.
    Formulation: Liquid. In PBS containing 50% glycerol and 0.01% sodium azide.
    Miscellaneous/General: Bradykinin (BK) is a nine-amino acid peptide produced by kallikrein cleavage of kininogen precursor proteins in tissue and plasma, and is an important regulator of vascular and pain responses to tissue injury. Two receptors (B1 and B2) have been identified as mediators of BK signaling, and are both seven-transmembrane domain-containing GPCRs. The B2 receptor is constitutively expressed in smooth muscle and neurons, whereas B1 expression is induced following injury. B2 receptors signal via Gq alpha subunits, leading to activation of phospholipase Cbeta, hydrolysis of PI, and an intracellular increase in free calcium, although coupling through Gi, Gs, and G12/13 has also been observed.