产品名称：PGD2 receptor (DP1), pAb
Alternative Name: PTGDR, prostaglandin D2 receptor
Long Term Storage: -20°C
Immunogen: Synthetic peptide corresponding to the sequence near the N-terminus of rat PGD2 receptor (DP1).
Application: ELISA (Membrane)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes rat PGD2 receptor (DP1). Predicted MW of ~40kDa. Predicted species reactivity based on epitope sequence homology: mouse.
Purity Detail: Peptide affinity purified.
Formulation: Liquid. In PBS containing 50% glycerol and 0.01% sodium azide.
Miscellaneous/General: The conversion of arachidonic acid to prostaglandin H2 (PGH2) by cyclooxygenase (COX) enzymes is the first step in the synthesis of prostanoids. Prostaglandin D2 (PGD2) is synthesized from PGH2 by the action of PGD synthase, and its actions in vasodilation and platelet activation are mediated via activation of two identified G-protein coupled receptors (GPCRs): DP1 and DP2 (formerly CRTH2). Both DP1 and DP2 receptors are coupled to Gs alpha subunits, resulting in increased adenylyl cyclase activity and cAMP production upon agonist binding.