产品名称：Oct-3/4, mAb (9B7)
Alternative Name: POU5F
Long Term Storage: -20°C
Immunogen: Recombinant human Oct4 (aa 1-360).
Application: Western Blot (1:5000)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human Oct-3/4. Detects a band of ~39kDa (full length) by Western blot.
Purity Detail: Protein G affinity purified.
Formulation: Liquid. In PBS, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Miscellaneous/General: Oct4 is a members of Oct family of transcription factors which specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids. These include the POU homeodomain and the POU-specific domain. Both are required for DNA binding and are involved in protein-protein interactions. Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation. Oct4 is renowned as a transcription factor expressed by undifferentiated embryonic stem cells and embryonic germ cells.