上海浩洋生物科技有限公司

 Jnk1, mAb (2C6)
  • Jnk1, mAb (2C6)
  • Jnk1, mAb (2C6)

    参考价格: ¥4350.00
    品  牌:ENZO
    产品型号:ADI-905-894-100 (100 ul)
    所在地区:上海
    上架时间:2013年03月04日
    留言咨询
    与企业取得联系时请告知该信息获取自中国教育装备采购网
    我要分享
    详细说明

    Jnk1, mAb (2C6)
    产品名称:Jnk1, mAb (2C6)
    规格:100 ul
    货号:ADI-905-894-100
    厂商:ENZO
    产品介绍:
    Alternative Name: SAPK, MAPK8
    Clone: 2C6
    Host: Mouse
    Isotype: IgG1
    Long Term Storage: -20°C  
    Immunogen: Recombinant human Jnk1 (aa 1-384).
    Application: Western Blot (1:1000)
    Optimal conditions must be determined individually for each application.
    Specificity: Recognizes human Jnk1. Detects a band of ~45kDa (full length) by Western blot.
    Purity Detail: Protein G affinity purified.
    Formulation: Liquid. In PBS, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
    Miscellaneous/General: JNK1 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. JNK1 is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of JNK1 by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. JNK1 is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of JNK1 gene suggested that it play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.