产品名称：Vimentin (human), (recombinant)
Alternative Name: VIM
Long Term Storage: -80°C
MW: ~86kDa (including GST-tag)
Source: Produced in E. coli.
Formulation: Liquid. In 50mM Tris-HCl, pH 7.5, containing 10mM L-glutathione (reduced).
Purity Detail: Purified by multi-step chromatography.
Western Blot (control)
Optimal conditions must be determined individually for each application.
Miscellaneous/General: Vimentin is an ~58 kDa intermediate filament protein distributed widely in the cytoplasm and is phosphorylated by several protein kinases in vitro. Components of intermediate filaments provide information on the origin of vertebrate cells. Antibody to vimentin can be used as to identify the vimentin subclass of intermediate filaments. Vimentin is a widely expressed protein that is thought to be involved mainly in structural processes, such as wound healing. Researchers have also determined that activated human macrophages secrete vimentin into the extracellular space, and overproduction of vimentin has been associated with cellular senescence.