产品名称：Osteoprotegerin, mAb (98A1071)
Alternative Name: OPG
Long Term Storage: -20°C
Immunogen: Synthetic peptide corresponding to the sequence near the N-terminus of human OPG (osteoprotegerin).
Application: Western Blot (1µg/ml AP, 1µg/ml ECL)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human OPG. Detects a band of ~55kDa & ~110kDa by Western blot.
Purity Detail: Protein G affinity purified.
Formulation: Liquid. In PBS containing 0.2% gelatin and 0.05% sodium azide.
Miscellaneous/General: Osteoprotegerin (OPG) is a secreted glycoprotein belonging to the TNF receptor (TNF-R) superfamily that functions as a decoy receptor for RANK-Ligand (RANKL/OPGL). Unlike other TNF-Rs, OPG lacks a membrane-anchoring hydrophobic domain and lacks any apparent cell-associated signaling capability. OPG secreted by osteoblasts competes with RANK (expressed on osteoblast precursors) for binding to RANKL, blocking osteoclastogenesis and increasing bone density.