产品名称：FADD, mAb (1F7)
Alternative Name: MORT1, Fas (TNFRSF6)-associated via death domain
Long Term Storage: -20°C
Immunogen: Recombinant human FADD.
Application: Western Blot (1µg/ml, ECL)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human and mouse FADD. Detects a band of ~28kDa by Western blot.
Purity Detail: Protein A affinity purified.
Formulation: Liquid. In PBS containing 50% glycerol.
Miscellaneous/General: Fas-associating death domain containing protein (FADD)/MORT1 serves as a signal transducer of Fas-induced apoptosis. Through its amino-terminal death effector domain (DED), FADD binds to cytosolic proteins such as TRADD, a cytosolic death domaincontaining protein that asssociates with the cytosolic portion of TNF receptor, or MACH/FLICE/caspase-8, a protease with sequence homology to ICE-CED-3 protease family, in order to transduce the death signal.