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 DcR2, pAb
  • DcR2, pAb
  • DcR2, pAb

    参考价格: ¥4350.00
    品  牌:ENZO
    产品型号:ADI-AAP-371-E (100 ug)
    所在地区:上海
    上架时间:2013年03月04日
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    DcR2, pAb
    产品名称:DcR2, pAb
    规格:100 ug
    货号:ADI-AAP-371-E
    厂商:ENZO
    产品介绍:
    Alternative Name: DR, Death Receptor, TRAIL R4
    Host: Rabbit
    Long Term Storage: +4°C  
    Immunogen: Synthetic peptide corresponding to a portion of human DcR2.
    Application: Immunocytochemistry (10µg/ml)
    Immunohistochemistry
    Western Blot (1:1000-1:2000)
    Optimal conditions must be determined individually for each application.
    Specificity: Recognizes human, mouse and rat DcR2. Detects a band of ~36kDa by Western blot.
    Purity Detail: Peptide affinity purified.
    Formulation: Liquid. In PBS containing 0.02% sodium azide.
    Miscellaneous/General: Decoy receptors (DcRs) are signaling-deficient receptors for certain members of the TNF family of cytokines, including TRAIL/Apo2L and FasL. Functional TRAIL receptors such as DR4 and DR5 transmit apoptotic signals via their intracellular death domains. In contrast, three identified TRAIL decoy receptors (DcR1, DcR2, and osteoprotegerin/OPG) completely or partially lack the signaling death domain, and/or are secreted from cells and unable to transmit intracellular signals. Thus, expression of DcRs promotes survival by sequestration of apoptotic ligands. A fourth identified decoy receptor, DcR3, binds both FasL and the vascular endothelial cell growth inhibitor (VEGI), inhibiting Fas and DR3 death signals.