Alternative Name: TNF receptor-associated factor
Long Term Storage: -20°C
Immunogen: Recombinant mouse TRAF6 (N-terminal fragment).
Application: Immunoprecipitation (2-4µg/100-500 µl cell extract from 5x106 cells)
Western Blot (1µg/ml, ECL)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes mouse TRAF6. Detects a band of ~58kDa by Western blot.
Purity Detail: Immunoaffinity purified.
Formulation: Liquid. In PBS containing 50% glycerol.
Miscellaneous/General: TRAF proteins are multifunctional signal adaptors that are involved in the activation of the kinase cascades which activate c-Jun N-terminal kinase, p38 mitogen activated protein kinase, and the transcription factor NFkappaB. Members of the TRAF family form homodimers as well as heterodimers, resulting in extensive diversity and specificity to their function in signal transduction pathways.