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 c-FLIP, pAb
  • c-FLIP, pAb
  • c-FLIP, pAb

    参考价格: ¥4350.00
    品  牌:ENZO
    产品型号:ADI-AAP-440-E (100 ug)
    所在地区:上海
    上架时间:2013年03月04日
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    c-FLIP, pAb
    产品名称:c-FLIP, pAb
    规格:100 ug
    货号:ADI-AAP-440-E
    厂商:ENZO
    产品介绍:
    Host: Rabbit
    Long Term Storage: +4°C  
    Immunogen: Synthetic peptide corresponding to the sequence near the N-terminus of human c-FLIP6. The sequence conserved among all c-FLIP variants.
    Application: Immunocytochemistry (5µg/ml)
    Western Blot (0.5-1.0µg/ml)
    Optimal conditions must be determined individually for each application.
    Specificity: Recognizes human, mouse and rat c-FLIP. Detects a band of ~28-58kDa by Western blot.
    Purity Detail: Peptide affinity purified.
    Formulation: Liquid. In PBS containing 0.02% sodium azide.
    Miscellaneous/General: The cellular FLICE-like inhibitory protein, cFLIP, is a cellular homologue of the viral protein, vFLIP. cFLIP contains two death effector domains (DEDs) and is expressed as either a short or long splice variant called cFLIPs and cFLIPL, respectively. cFLIP acts as a caspase-8 dominant negative regulator, blocking apoptosis induced by the oligimerization of the adapter protein, FADD. cFLIP interacts with FADD and caspase-8 through their respective DEDs.