上海浩洋生物科技有限公司

 GSK-3α/β, mAb (1H8)
  • GSK-3α/β, mAb (1H8)
  • GSK-3α/β, mAb (1H8)

    参考价格: ¥2550.00
    品  牌:ENZO
    产品型号:ADI-KAM-ST002-D (50 ug)
    所在地区:上海
    上架时间:2013年03月05日
    留言咨询
    与企业取得联系时请告知该信息获取自中国教育装备采购网
    我要分享
    详细说明

    GSK-3α/β, mAb (1H8)
    产品名称:GSK-3α/β, mAb (1H8)
    规格:50 ug
    货号:ADI-KAM-ST002-D
    厂商:ENZO
    产品介绍:
    Alternative Name: glycogen synthase kinase
    Clone: 1H8
    Host: Mouse
    Isotype: IgG2b
    Long Term Storage: -20°C  
    Immunogen: Recombinant Xenopus GSK-3β.
    Application: Immunocytochemistry
    Immunohistochemistry
    Western Blot (1:1000, colorimetric)
    Optimal conditions must be determined individually for each application.
    Specificity: Recognizes human, mouse, rat, bovine, dog, hamaster, monkey, pig, rabbit and sheep GSK-3α/β. Detects bands of ~51 and ~47kDa by Western blot.
    Purity Detail: Protein G affinity purified.
    Formulation: Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
    Miscellaneous/General: Glycogen Synthase Kinase 3beta (GSK-3beta) is a unique serine/threonine kinase that is inactivated by phosphorylation. In response to insulin binding, PKB/AKT phosphorylates GSK-3beta on serine 9, which prevents GSK-3beta from phosphorylating glycogen synthase. Unphosphorylated glycogen synthase is active and able to synthesize glycogen. GSK-3beta is also unique in that it requires a substrate that has been phosphorylated by a distinct kinase before it can phosphorylate the substrate. This phosphate priming mechanism explains why phosphorylation of serine 9 inactivates GSK-3beta.
    ENZO ADI-KAM-ST002-D GSK-3α/β, mAb (1H8) 50 ug 2550
    ENZO ADI-KAM-ST002-F GSK-3α/β, mAb (1H8) 200 ug 5100