Alternative Name: ribosomal protein S6 kinase, MAPKAPK1
Long Term Storage: -20°C
Immunogen: Synthetic peptide corresponding to a portion of mouse RSK2.
Application: Immunohistochemistry (paraffin sections)
Western Blot (1µg/ml, colorimetric)
Optimal conditions must be determined individually for each application.
Specificity: Recognizes human, mouse, rat, bovine, dog, chicken, guinea pig, monkey, pig, rabbit and sheep p90/RSK2.
Purity Detail: Protein A affinity purified.
Formulation: Liquid. In PBS, pH 7.2, containing 50% glycerol and 0.09% sodium azide.
Miscellaneous/General: Ribosomal protein S6 kinase II (RSK2) is a protein serine/threonine kinase that was originally detected by its ability to catalyze the multi-site phosphorylation of the 40S ribosomal protein S6 in vitro. One of the important substrates of RSK may be the Glycogenbinding subunit of Protein phosphatase-1, which when phosphorylated by RSK, appears to activate Protein phosphatase 1. This results in increased dephosphorylation and activation of Glycogen synthase to enhance Glycogen synthesis.