上海浩洋生物科技有限公司

 OxPAPC
  • OxPAPC
  • OxPAPC

    参考价格: ¥3024.00
    品  牌:invivogen
    产品型号:tlrl-oxp1 (1 mg)
    所在地区:上海
    上架时间:2013年03月18日
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    OxPAPC
    产品名称:OxPAPC
    规格:1 mg
    货号:tlrl-oxp1
    厂商:invivogen
    产品介绍:
    Working concentration: 30 µg/ml
    Endotoxin level: <0.125 EU/mg
    Solubility: 1 mg/ml in culture medium or chloroform
    OxPAPC is provided as a solid and shipped at room temperature. Store at -20°C. Solid product is stable 1 year at -20°C. Aliquots of OxPAPC resuspended in chloroform can be stored at -70°C for 3 months. Avoid repeated freeze-thaw cycles.
    OxPAPC is generated by the oxidation of 1-palmitoyl-2-arachidonyl-sn- glycero-3-phosphorylcholine (PAPC), which results in a mixture of oxidized phospholipids containing either fragmented or full length oxygenated sn-2 residues. OxPAPC has been shown to inhibit the signaling induced by bacterial lipopeptide and lipopolysaccharide (LPS). It acts by competing with CD14, LBP and MD2, the accessory proteins that interact with bacterial lipids, thus blocking the signaling of TLR2 and TLR4 [1, 2].